By Janice Lloyd, USA TODAY
Another drug is getting a second life because of desirable
side effects.
Botox was originally approved by the Food and Drug Administration
to reduce eye spasms. Then the world realized it also made
people look younger by eliminating wrinkles.
Human growth hormone was intended for children
with growth disorders, but older people seeking the fountain
of youth and athletes wanting a boost started finding illegal
suppliers of HGH for muscle growth and overall toning.
The latest development involves Lumigan, a drug
Allergan produced to treat glaucoma. The disease can lead
to blindness if left untreated. The medication decreases pressure
within the eye either by slowing the production of a fluid
in the eye or by increasing fluid drainage. One of the side
effects of Lumigan is longer, thicker and darker eyelashes.
Allergan developed a spinoff called Latisse,
which the FDA approved for eyelash enhancement in December.
Lumigan drops are used in the eyes; Latisse is applied to
the upper eyelid. Bimatoprost is the active ingredient common
to both drugs.
"Forget about fake lashes, they end up
on your cheeks," says Liz Weber of Washington, D.C. "This
is my favorite stuff ever."
Weber, 52, was distressed about having short
lashes and bald spots, a condition called hypotrichosis. Her
dermatologist told her the condition can be persistent after
menopause. Weber had used fake eyelashes and was ready to
try eyelash extenders when she found out about Latisse.
"Now, my daughter calls them my Bambi lashes,"
she says.
Dermatologists say customers are lining up.
Richard Glogau, a member of the American Academy of Dermatology
who practices in San Francisco, says he got his first shipment
of 60 boxes three weeks ago and was sold out within a week.
A box is a month's supply.
"I had no idea how big eyelashes were with
women until this came along," Glogau says. "The
response has been impressive. I was a little taken aback at
first, but they report that their eyelashes got thinner as
they got older or they were too blond."
One of the warnings for both Lumigan and Latisse
is possible change in pigmentation of the eyelid and darkening
of the iris. Though not harmful, once change of the iris does
occur, it is permanent.
Weber's dermatologist, Marilyn Berzin of Dcdermdocs
in Washington, D.C., says she believes Latisse is safe and
is not likely to alter the iris color because it's not applied
directly to the eyes.
Still, Andrew Iwach, a glaucoma specialist and
spokesman for the American Academy of Ophthalmology, cautions
people who have eye inflammation, glaucoma or macular edema
to consult with their eye doctor before using Latisse.
It costs about $4 a day, and insurance doesn't
cover it. Berzin says that after 16 weeks of daily application,
it is possible to cut back to once or twice a week for maintenance
of the lashes. If you discontinue use altogether, eyelashes
return to their previous appearance.
David Pyott, chairman of the board and CEO of
Allergan, expects Latisse to ultimately equal the cosmetic
use of Botox. "Botox is for an aging population,"
he says. "Latisse can benefit anyone," including
cancer patients who have had chemotherapy and lost their lashes.
Their lashes eventually will grow back without Latisse.
The FDA did not approve Latisse for people under
18 or for pregnant or lactating women.
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